Total number of Shares in Issue: 3,990,074 Ordinary Shares of £0.05 each
Number of Shares in public hands: 2,576,334 Ordinary Shares of £0.05 each
Percentage of Shares in public hands: 64.57%

The ISIN Reference is GB00BPFJXS57.

The Share Information above is correct as at: 25/05/2018

The interests of the Directors and their immediate families, civil partners (as defined in the Civil Partnership Act 2004) and persons connected with them (within the meaning of sections 252 to 254 of the Act), all of which, unless otherwise stated, are beneficial as at 20/04/2018 are as follows:

Name Number of Issued Ordinary Shares Percentage of Issued Ordinary Shares
Sir Richard Dearlove 0 0%
Thomas Ilube 1,382,112 34.64%
Dr David Secher 26,365 0.66%
Ruth Anderson 0 0%
Professor David Stupples 5,263 0.13%
Gordon Matthew 0 0%
Andrew Gueritz 0 0%

(Thomas Ilube’s shareholding is made up of 1,251,668 shares held by him personally and 130,444 held by Beaufort Nominees Limited on his behalf)

In addition to the above, as at 25/05/2018, the Directors are aware that the following Shareholders will be interested, directly or indirectly, in 3 per cent or more of the votes able to be cast at general meetings of the Company.

Name Number of Ordinary Shares Percentage of Issued Ordinary Shares
Brenlen Jinkens 348,343 8.73%
Moulton Goodies Ltd 289,474 7.25%
Steven Gee 228,852 5.74%
Maurice Zimmerman 215,694 5.41%
Marlborough Nano Cap Growth Fund 185,185 4.64%
Share Nominees Limited 126,706 3.18%
John Taysom 126,514 3.17%

In addition, the Directors hold the following shares under option:

Name Date of grant Number of Ordinary Shares under option Exercise Price Vesting Conditions Expiry Date
Sir Richard Dearlove 15/09/16 13,158 £1.90 (1) 15/09/26
Sir Richard Dearlove 25/05/18 6,757 £3.70 (1) 25/05/28
Thomas Ilube N/a Nil Nil N/a N/a
Dr David Secher 18/07/14 15,000 £0.54 (1) 17/07/24
Ruth Anderson N/a Nil Nil N/a N/a
Professor David Stupples 18/07/14 35,000 £0.54 (1) 17/07/24
Gordon Matthew 20/07/15 5,000 £1.90 (1) 19/07/25
Andrew Gueritz N/a Nil Nil N/a N/a

(1) Option Shares to vest in three equal tranches on the first, second and third anniversary of the date of grant.

Total number of share options granted to Directors: 74,915

Total number of share options granted to staff: 64,500

The amount and percentage of immediate dilution assuming full exercise of share options on conversion:

Existing share capital: 3,990,074

Total number of shares under option: 139,415

Total dilution: 139,415

Fully Diluted Share Capital = 4,129,489

Percentage of dilution = 3.38%